| 1. | It delivers the false ? folding peptides for presentation to proteasomes in normal cells , while in tumor cells it acts as main tumor - resistant antigen , inducing specific immune response . recent research found that grp94 also relates with cell cycles , differentiation and apoptosis 此外发现它还具有抗原提呈作用,在正常细胞中参与折叠错误蛋白到蛋白酶体的提呈;在肿瘤细胞中作为主要的肿瘤排斥抗原,引发针对该肿瘤细胞的特异性免疫反应。 |